This is TB's moment and it must be seized
Two scientific breakthroughs and a global meeting mean there is an opportunity to move TB from the doldrums.
Jeremy Farrar
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Treatments for recurring TB infection failing low-income countries, study finds
The standard approach to re-treating tuberculosis (TB) in low- and middle-income settings is failing, according to research funded by the Wellcome Trust. In a study published…
New genetic discovery could improve diagnosis of childhood TB
A distinctive genetic 'signature' found in the blood of children with tuberculosis (TB) offers new hope for improved diagnosis of the disease.
Rapid, low-cost test for multidrug-resistant TB gains WHO endorsement
A rapid, low-cost test for diagnosing tuberculosis (TB) - including multidrug-resistance - has been endorsed by The World Health Organization (WHO) for use in resource-poor…
First direct evidence links TB infection in cattle and local badger populations
Transmission of tuberculosis between cattle and badgers has been tracked at a local scale for the first time, using a combination of bacterial whole-genome DNA sequencing and…
Genetic variant offers protection against TB and leprosy
A study into why some people are more resistant than others to diseases such as tuberculosis and leprosy has identified a new genetic variant which affects susceptibility to…
Funding for late-stage development of a tuberculosis vaccine candidate that could be the first in 100 years if proven effective
Wellcome and the Bill & Melinda Gates Foundation announce funding to advance a tuberculosis (TB) vaccine candidate through a Phase III clinical trial.
TB trial highlights the challenges of introducing new childhood vaccine
A new vaccine to combat tuberculosis is less effective at stimulating an immune response when administered to Gambian infants in combination with the routine immunisation…
The world’s first tuberculosis vaccine in 100 years could be in sight
The world needs a new vaccine to fight tuberculosis (TB). A new multimillion-pound global study funded by Wellcome and the Bill & Melinda Gates Foundation could provide a…
Late-stage trial for tuberculosis vaccine candidate underway in South Africa
The Phase 3 clinical trial to assess the efficacy of the M72/AS01E tuberculosis (TB) vaccine candidate is now underway, with first doses given in South Africa, where TB takes…
Launch of new R1.2-billion KwaZulu-Natal research powerhouse
In a bold move to improve the health of people locally and globally, two research giants in KwaZulu-Natal (KZN) are joining forces to form a ground-breaking new…
Wellcome statement in response to the WHO Global TB Report 2023
Wellcome statement in response to the World Health Organization Global Tuberculosis Report 2023.
Genome study identifies genetic variant linked to tuberculosis susceptibility in Africans
Scientists have identified a genetic variant that increases susceptibility to tuberculosis (TB) in African populations using a technique known as a genome-wide association (…
Liz's story: how she transformed HIV testing in Africa
As a world-renowned scientist, Liz had to navigate plenty of obstacles throughout her career – from getting support for early-stage research ideas to influencing…
Tuberculosis is curable and preventable – why do millions still die?
Over the last 100 years, tuberculosis research has saved millions of lives but it has failed to curb the epidemic. While some recent scientific developments are promising,…
From drug discovery to delivery, we need to do more to fight infectious diseases
The way we tackle infectious diseases is largely led by countries and organisations in the global north, competition and profit. How can we create a better research and…
New laptop program can identify drug resistance from bacterial genomes
Scientists have developed an easy-to-use computer program that can quickly analyse bacterial DNA from a patient’s infection and predict which antibiotics will work, and which…
How are diet, food and climate change connected?
Climate change is driven by and impacts the world’s food systems. But, changing how we produce our food – as well as what we eat – could help protect our planet and our…
Simge Eva Dogan
Media statement in response to the World Health Organization’s Global tuberculosis report 2022
Charlie Weller, Head of Prevention at Wellcome, responds to the publication of the World Health Organization's Global tuberculosis report 2022.
Wellcome appoints new Director of Infectious Disease
Alexander Pym, an infectious disease expert with experience across academia, clinical settings and industry, will lead Wellcome’s work on infectious disease, supporting…