Our impact

Wellcome supports science to solve the urgent health challenges facing everyone. Here we share the impact of that work through films and articles: the science, the people behind it, and the lives it changes.

Lisa
So when Lulu was born, she had lots of gastro problems. She couldn't feed properly.

Phil
She wasn't reaching her milestones.

Fortunate Machingura
You just got this feeling something's not right. The challenge is still on just basic understanding of the impacts of heat on pregnancy.

Remi Pereszczak
I got diagnosed at two years old with a very rare extreme genetic condition. I feel like I was missing out a lot.

Paul Kazyoba
Passion is one of the drivers to be a successful research scientist.

Archive news report
Compiled last year, the human genome finally goes public. It really was a triumphal celebration.

Claire Booth
These amazing therapies, which were just dreams 30 years ago, are now reality for quite a lot of patients.

Doug Turnbull
The Wellcome Trust gave me a ring and said, we're not going to give you the grant, we're going to make you a Wellcome Centre. And it was totally transformational.

Amy Hardy
The challenge was how do we create a therapy that is more appealing and easier to use that would improve access, experience and outcomes.

Gareth Barnes
I never imagined that this technology was possible. I always thought it was a pipe dream.

Paul Kazyoba
That demonstrates the commitment the Wellcome Trust has in advancing public health in the world.

Fortunate Machingura
I really hope that these very simple interventions can change lives.

Helen Firth
Behind every diagnosis, there's a child and a family.

Speaker of the House (archive)
The ayes to the right, 382.

Kat
It really is a once in a lifetime moment, to be part of something where law is changed for the sake of medical advancement.

Matthew Brookes
I am excited for the future. I hope that in a few years' time, we'll see patients starting to benefit and lives being changed.

Liberty Jones
It's like having a cloud on your head actually.

Exhibition visitor (Sickle Cell)
It's the difference between health and wellness and sickness and pain.

Lisa
Studies like this have to keep happening because without them, loads more parents are going to be just left wondering. So it really has changed us and changed our lives.

What impact looks like 

Remi's childhood was spent in and out of hospital with a rare immune condition. Now he is at university, making friends, free from most of his medication. Between those two lives is a gene therapy no one had tried before, built on decades of research. 

Remi’s story is one of many. A family with a diagnosis, after years in the dark. A community that changed how the world responds to epidemics. A drug redesigned, making it easier for young children to swallow. Different science, different people, different places. The same question: what does it take for research to change someone's life? 

These stories run from a single cell to whole communities, from discoveries making a difference today to questions science is still working to answer.

"Science creates opportunities to improve health. But those opportunities only change lives when communities are involved, policymakers act on the evidence and health systems can deliver. This work from science to impact is what Wellcome supports – and these stories show what it looks like.”

John-Arne Røttingen

Chief Executive Officer

Wellcome

Connect with John-Arne:

"Science creates opportunities to improve health. But those opportunities only change lives when communities are involved, policymakers act on the evidence and health systems can deliver. This work from science to impact is what Wellcome supports – and these stories show what it looks like.”

The numbers behind the mission

90 years
backing science to improve health
3 billion+ british pounds
investment over 30 years that has transformed genomics research
2000+ researchers
trained through DELTAS Africa to strengthen Africa-led science

Read the stories 

Go deeper: the research, the evidence and the people at the centre of each story.

Watch the films 

Changing lives through science. Watch the documentaries.

video duration

Mitochondrial diseases are progressive, life-limiting and passed from mother to child. For decades, there was no way to break that cycle. Then a team in Newcastle developed an IVF technique that could.

This film follows the 25-year journey from laboratory research to a vote in the House of Commons – where the UK became the first country in the world to permit mitochondrial donation. So far, eight healthy babies have since been born through the technique.

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Learn more 

About us

We're a global charitable foundation established in 1936, working towards a healthier future for everyone.  

Our priorities

Wellcome improves health for everyone by supporting discovery research into life, health and wellbeing, and taking on three worldwide health challenges: mental health, infectious disease and climate and health.

Insights

News, opinions and reports on the issues Wellcome cares about, the research Wellcome funds and the way we work.