The trypanosome flagellar pocket – functions and adaptations in differentiation, pathogenicity and immune evasion


  • Dr Samuel Dean

    University of Oxford

Project summary

Sam began his Fellowship in August 2010. His project investigates the shape, form and biochemistry of the trypanosome flagellar pocket and how this relates to the pathogenicity of the parasite. Sam’s project arose from some surprising discoveries he made during his PhD regarding the response of trypanosome surface molecules to environmental change. He is currently working with Professor Keith Gull in the Dunn School of Pathology, University of Oxford, to learn techniques in electron microscopy and tomography. Sam will also spend time with Professor Markus Engstler at the University of Wurzburg, Germany, to learn advanced live cell imaging techniques.