Regulation of immune function by the transcription factor BACH2

Year of award: 2014


  • Dr Rahul Roychoudhuri

    Babraham Institute

Project summary

Rahul's research aims to understand how a class of proteins called transcription factors guide the behaviour of T lymphocytes. T lymphocytes powerfully regulate immune function by differentiating into specialised cellular lineages that either drive or constrain immune reactions. Based at the Babraham Institute in Cambridge, Rahul’s group applies diverse molecular biology, cellular immunology and functional genomics approaches to investigate how transcription factors regulate lymphocyte behaviour in the context of infections, autoimmunity and cancer. This research aims to identify targets for a new class of therapies that will powerfully manipulate immune function in patients with autoimmunity, chronic infection and cancer.