Quantitative proteomic dissection of genetic aberrations in PDAC development

Christopher will start his Fellowship in the laboratory of Dr Claus Jorgensen at the Institute of Cancer Research in London, where he will be using cell-specific phosphoproteomics to investigate dynamic cell-cell communication between multiple cell types in pancreatic ductal adenocarcinoma (PDAC). In collaboration with Professor Doug Lauffenburger at MIT, the dual-cell phosphoproteomic data will be used to develop a computational understanding of cell-cell signalling across sequential genetic stages of PDAC development.