Molecular and functional analysis of antibody repertoire and proviral DNA in HIV-1-exposed seronegative individuals


  • Gladys Macharia

    KEMRI-Wellcome Trust Research Programme

Project summary

Gladys is interested in learning why not every exposure to HIV has the same outcome, why some people do not become infected, and why some people, when infected, do not progress to AIDS, or progress much faster than others. Her Fellowship will support research that is focused on a molecular and functional analysis of HIV-specific B-cell responses and proviral DNA in HIV-1-exposed seronegative individuals. This work will help to explain whether B cells play a role in protecting HIV-exposed seronegative individuals from infection with HIV.

This grant was awarded under the scheme's previous name of Master's Fellowships in Public Health and Tropical Medicine.