Mitotic spindle orientation and the mechanical tissue environment

Year of award: 2012


  • Dr Sarah Woolner

    University of Manchester

Project summary

Sarah's research aims to understand how cell behaviour in developing embryos is influenced by the external tissue environment. In particular, she is focusing on determining how cell division orientation is directed by mechanical tissue cues. The orientation of cell division plays a vital role in shaping and organising tissues and in determining cell fate.Sarah's lab is based in the Wellcome Trust Centre for Cell-Matrix Research at the University of Manchester.