Mechanism and regulation of antigen translocation during cross-presentation

Patrycja will begin her Fellowship in the laboratory of Professor Sebastian Amigorena at the Institut Curie in Paris, where she will work on antigen cross-presentation by dendritic cells. Patrycja's goal is to identify molecular machinery involved in the processing of exogenous antigens for presentation by MHC class I molecules, and to evaluate the role of innate receptors in regulating this process. The work will be carried out in collaboration with the laboratories of Professor Nir Hacohen at the Broad Institute, Boston, and Professor Caetano Reis e Sousa at the London Research Institute, CRUK.