Mechanism of multivalent lectin-carbohydrate interaction


  • Dr Yuan Guo

    School of Chemistry

Project summary

Yuan's research aims to understand how high-affinity binding between glycan-binding proteins (also known as lectins) and their specific sugar ligands is achieved through multivalent interaction. Such binding underpins a wide range of important biological recognition events closely associated with cancer metastasis, pathogen infectivity and immune regulation.