Lineage tracing as a strategy to resolve mechanisms of stem cell fate: from development and maintenance to disease and ageing

Professor Simons has a background in condensed matter physics but since 2005 has turned his expertise towards answering fundamental questions in stem cell biology. With this award, he will be using a combination of experimental and theoretical approaches to study how stem cells are regulated in tissue maintenance, development and disease. His work will focus on a wide range of biological systems, including the epidermis, neuroepithelia and gut.