Injury and repair of the peripheral nervous system: the role of neuregulin-ErbB signalling

Year of award: 2011


  • Prof David Bennett

    University of Oxford

Project summary

Professor Bennett employs a multidisciplinary approach, using techniques ranging from cellular models to patient cohorts, in order to gain a better understanding of how the peripheral nervous system responds to injury. His clinical interest in acquired and inherited peripheral neuropathies complements this research. His aim is to develop strategies to promote effective neural repair and prevent the development of deleterious consequences such as neuropathic pain. A key focus is the bi-directional signalling pathways between neurons and their associated glial cells which are essential for coordinating an effective response to neural injury. Professor Bennett's laboratory is currently focusing on the role of growth factors such as neuregulin in promoting neural repair.