Immune pathways in the intestine in health and disease
Year of award: 2011
Grantholders
Prof Fiona Powrie
University of Oxford
Project summary
Our intestines contain a huge number of microbes that play an important part in our health. In inflammatory bowel disease, the beneficial relationship we have with these bacteria breaks down, resulting in chronic and painful intestinal inflammation. Professor Powrie will be investigating how the 'dialogue' between the intestinal immune system and intestinal bacteria breaks down and why this leads to disease.