Determining the function of the transcriptional co-repressor RIP140 in skeletal muscle metabolic adaptation to exercise and insulin resistance

Joaquin is currently working in collaboration with Professor Janet Lord and Dr Andy Philp at the University of Birmingham and Dr Anastasia Kralli at the Scripps Research Institute, California, where he is studying the role of transcriptional co-repressors in the regulation of skeletal muscle metabolism and the development of metabolic diseases. The main aim of Joaquin's project is to uncover the molecular mechanisms by which exercise regulates co-repressor activity and to subsequently determine their role in the development and treatment of obesity and insulin resistance in humans.