Dealing with uncertainty in prenatal genomics: an international comparison study


  • Dr Celine Lewis

    Great Ormond Street Hospital for Children

Project summary

Technological advances in prenatal testing mean we can now identify more genetic conditions during pregnancy. This information can be helpful for parents in deciding how to manage their pregnancy, but because of the complexity of some of the information collected, it can cause uncertainty as it is difficult to interpret. Studies show some parents are prepared to tolerate some level of uncertainty but for others uncertainty during pregnancy causes anxiety and complicates decision-making. 

The aim of this research is to conduct a small study to look at how patients and health professionals in different countries deal with uncertainty during pregnancy. We will identify key research questions through consultation with experts and then develop and test the methods to answer those questions. Our findings will help to prepare for a larger international study.