Combined genetic and biochemical approaches to uncover and characterise redundant factors involved in late stages of recombinational repair

Year of award: 2014

Grantholders

  • Prof Anton Gartner

    University of Dundee

Project summary

Anton uses C. elegans as a model organism to study basic biological problems. Homologous recombination is needed for error free DNA repair and for meiotic recombination. Holliday Junctions are crucial recombination intermediates first postulated to exist more than 40 years ago. Anton focuses on how these junctions are processed both during recombinational repair and during meiosis.