Chemically functionalised aptamer-conjugated nanographene delivering microRNAs: on the road to brain cancer eradication?
Year of award: 2014
Grantholders
Dr Pedro da Costa
King's College London
Project summary
Building on his biochemistry background, Pedro will use his Fellowship to develop functionalised graphene-based nanocarriers for delivery of therapeutic molecules to brain tumours. Nanocarrier synthesis and functionalisation will be carried out at the laboratory of Dr Khuloud Al-Jamal (King's College London). Pedro will later join Dr Matthew Levy (Albert Einstein College of Medicine, New York), where he will develop aptamers for the targeting of the nanocarriers, while studies with brain cancer stem-like cells and tumour xenografts will be performed at the laboratory of Dr Steven Pollard (MRC Centre for Regenerative Medicine, Edinburgh).