Bridging the gap from type 2 diabetes genetics to functional mechanisms of disease

Anna's research is focused on the translation of genetic association signals for type 2 diabetes and glycaemic traits into molecular, cellular and physiological mechanisms. Anna is particularly interested in integrating genetic association data with human islet transcriptomic and genomic data to identify mechanisms for pancreatic islet dysfunction. Her work is highly translational and supports efforts to improve our ability to interpret genetic variation in genes implicated in diabetes risk, and to identify effective therapeutic targets for drug development. Anna is an active member of a number of international consortia investigating the genetic basis of type 2 diabetes and related glycaemic traits.