Adaptive immune-system structure and dynamics in health and autoimmune disease

Rachael's research focuses on understanding the immunological changes associated with autoimmune disease course. She will be working jointly between the laboratories of Professor Ken Smith (University of Cambridge) and Professor William Robinson (Stanford University). Rachael will use a combination of next-generation sequencing, experimental techniques and computational analyses to develop systems for probing autoantigen-specific B-cell population dynamics, and will use this knowledge to provide insights into autoimmune disease development.