Principal Research Fellowships (Closed)
Principal Research Fellowships are the most prestigious of our personal awards and provide long-term funding for researchers of international standing.
We’re changing our funding schemes
The way we fund research is changing to support our new strategy.
Scheme at a glance
This scheme is now closed
- Lead applicant career stage:
- Administering organisation location:
- UK, Republic of Ireland
- Funding amount:
Salary and research expenses covered
- Funding duration:
5 or 7 years (see the ‘What we offer’ section on this page for an update on renewals)
Key dates
This scheme will close in 2021. You can express an interest in this award at any time but the final deadline for submitting full applications is 1 July 2021.
Who can apply
You can apply for a Principal Research Fellowship if you're a researcher of international standing with an established track record in research at the highest level. You must have:
- sponsorship from an eligible host organisation in the UK or Republic of Ireland
- a research project that is within our scientific remit.
Who can't apply
You can't usually apply if you:
- hold an established post in the UK or Republic of Ireland – we're willing to consider a preliminary application if you have a strong justification for moving to a different organisation
- are currently applying for another Wellcome Trust fellowship.
If you've already been unsuccessful with a full application for this scheme, please contact us before you apply again.
You can't apply to carry out activities that involve the transfer of grant funds into mainland China.
What we're looking for
This award is particularly suitable for senior research scientists who:
- want to work in the UK or Republic of Ireland but are currently based in a different country
or
- currently hold Senior Research Fellowships in the UK or Republic of Ireland.
When we look at your application, we'll assess:
- your track record and standing in the field
- the quality and importance of your research question(s)
- your approach to solving these problems
- the suitability of your research environment.
What's expected of your host organisation
Your sponsor must guarantee that the host organisation will provide:
- the space and resources you need – this must be agreed at the application stage and made available from the start date through to the end date of your award
- an established post when the award ends.
See the 'What we offer' section for an update on renewals.
Other schemes
Investigator Awards in Science
Senior Research Fellowships
A Principal Research Fellowship is for seven years (or five if you hold a UK-based senior research fellowship).
New applicants who are awarded this fellowship will no longer be able to apply for a renewal at the end of their award.
Current Principal Research Fellows can apply for a renewal if their award ends on or before 31 October 2022. They must submit their application by 1 July 2021 (see the ‘key dates’ section on this page).
The fellowship can be held on a part-time basis. The award includes:
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We will fund the total cost of your salary for the entire period of the grant.
You should ask your host organisation to calculate this. It should reflect the skills, responsibilities and expertise needed to carry out the role, and include:
- your basic salary
- employer’s contributions, including any statutory obligations (eg National Insurance contributions if you’re based in the UK) and pension scheme costs
- any incremental progression up the salary scale
- locally recognised allowances such as London allowance.
You should exclude any Wellcome Trust fellowship supplement that was part of a previous grant.
You should allow for salary pay awards during Year 1. These should be based on pay awards already agreed: if you don’t know what the pay award is yet then use our inflation rate. For Year 1 include any known pay awards for this period or an assumed percentage equivalent to our current inflation rate of 2.0% if this hasn’t been confirmed.
From Year 2 onwards, we will automatically increase your salary, based on our current inflation allowance rates.
Your salary should normally be in the range of £75,000 to £100,000 a year. Your organisation will need to justify your salary if it’s higher than this.
Find out more about fellows working on a Wellcome grant.
Visa and work permit costs
If Wellcome is going to pay your salary on the grant, you can ask for visa costs to help you take up the post at your host organisation. You can also ask for:
- visa costs for your partner and dependent children
- Immigration Health Surcharge costs for you, your partner and dependent children if you will be in the UK for six months or more
- essential associated costs, such as travel to attend appointments at a visa application centre or embassy if you can justify these.
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We will provide:
- a Distinction Award of up to £50,000 based on your experience
- the extra employer's contributions needed to cover the supplement.
We won’t normally provide a supplement if you are employed on a clinical academic scale.
We will add this supplement to your award – you do not need to add it to your application.
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If you have to move to take up the post at your host organisation, you can ask for £1,000. You'll need to justify this.
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- basic salary
- employer’s contributions, including any statutory obligations (eg National Insurance contributions if you’re based in the UK) and pension scheme costs
- Apprentice Levy charges for UK-based salaries
- any incremental progression up the salary scale
- locally recognised allowances such as London allowance.
Staff salaries should be appropriate to skills, responsibilities and expertise. You should ask your host organisation to use their salary scales to calculate these costs, which should include:
You should allow for salary pay awards during Year 1. These should be based on pay awards already agreed: if you don’t know what the pay award is yet then use our inflation rate.
From Year 2 onwards, you should use your organisation’s current pay rates. We’ll provide a separate inflation allowance for salary inflation costs.
Find out more about people working on Wellcome grant.
We may make a contribution towards the salary of departmental technicians funded by Research England and its equivalents in Scotland, Wales and Northern Ireland. You will need to provide a full audit record of their time on your project.
- visa costs for the person's partner and dependent children
- essential associated costs, such as travel to attend appointments at a visa application centre or embassy if you can justify these
- Immigration Health Surcharge costs for the person, their partner and dependent children if they will be in the UK for six months or more.
You can ask for funding for research staff on your grant. There is no set limit to the number of staff, but usually it should be no more than 5 or 6. If you’re doing fieldwork or clinical studies in a low- or middle-income country, we’ll consider requests for more research staff.
We don't provide studentship stipends.
Visa and work permit costs
If you have named people on your grant whose salaries will be funded by Wellcome, you can ask for visa or work permit costs to help them take up their posts at the host organisation. You can also ask for:
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We will pay for the materials and consumables you need to carry out your proposed research, including:
- laboratory chemicals and materials (eg reagents, isotopes, peptides, enzymes, antibodies, gases, proteins, cell/tissue/bacterial culture, plasticware and glassware)
- associated charges for shipping, delivery and freight
- project-specific personal protective equipment (PPE) that is above the standard expected for the setting.
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You can ask for funds to buy animals if they are essential to your project. We will also fund the charge-out rates for animal house facilities if your organisation uses full economic costing methodology. These costs include:
- running costs (including animal maintenance, any experimental procedures, licences and relevant staff training)
- appropriate estates costs
- cage and equipment depreciation costs, but not building depreciation costs.
We may not pay the full charge-out rate for an animal house facility if we've provided significant funding towards the infrastructure and/or core support of the facility.
If your organisation doesn’t use full economic costing methodology to establish charge-out rates for animal house facilities, you can ask for funds to cover:
- the cost of buying animals
- running costs (including animal maintenance, any experimental procedures, licences and relevant staff training)
- staff costs, eg contributions towards the salaries of animal house technicians.
We won’t provide estates or depreciation costs.
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Equipment purchase
You can ask for items of equipment that are essential to your proposed research project. Costs may include purchase, delivery, installation, maintenance and training, where necessary.
We will cover VAT and import duties if:
- the usual UK exemptions on equipment used for medical research don’t apply
- you’re applying from a non-UK organisation, and you can show these costs can’t be recovered.
You can ask for larger items of equipment if they're not available at your host organisation.
If a complete piece of equipment costs £100,000 or more, we expect a contribution of at least 25 per cent from the host organisation or another source.
In some cases we may expect a larger contribution. We’ll discuss this with you after we’ve assessed your application.
Contributions can include benefits in kind, such as refurbishment or the underwriting of a key support post.
Equipment maintenance
We will cover maintenance costs for equipment if:
- you are requesting it in your application
- it is existing equipment that is:
- funded by us or another source
- essential to the proposed research project
- more than five years old
- cost effective to keep maintaining it.
We won’t cover maintenance costs for equipment if there is a mechanism in place to recoup these costs through access charges.
Computer equipment
We will cover the cost of one personal computer or laptop per person up to £1,500.
We won't pay for:
- more expensive items, unless you can justify them
- installation or training costs.
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You can ask for the cost of access to shared equipment or facilities if they’re essential to your research project. These may include materials and consumables, plus a proportion of:
- maintenance and service contracts
- staff time costs for dedicated technical staff employed to operate the equipment or facility.
We don’t cover the costs of:
- estates and utilities
- depreciation or insurance
- other staff eg contributions towards departmental technical, administrative and management staff time.
If the facilities or equipment were paid for by a Wellcome grant, you can only ask for access charges if:
- the grant has ended
- any support for running costs and maintenance contracts has ended.
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- Fellow – £2,000 a year
- Research staff employed on your grant – £1,000 each a year.
- Wellcome is paying your salary
- the conference is directly related to your research
- the caring costs are over and above what you'd normally pay for care
- the conference organiser and your employing organisation are unable to cover the costs.
- the cost of low carbon travel where practical, even if it's more expensive (for example travelling by train instead of flying)
- project-related resources or activities that provide an alternative to travel, such as video conferencing, communication and file-sharing software
- costs to offset the carbon emissions of the journeys you make.
- organisation-wide video conferencing packages
- high-speed broadband
- HD screens.
Travel costs
Conference attendance
You can ask for a contribution towards the costs of attending scientific and academic meetings and conferences, including registration fees and the costs to offset the carbon emissions of your travel. The limits are:
You’ll need to specify the amount you’re requesting for each person.
You can also ask for costs to cover caring responsibilities if you or any staff employed on your grant attend a conference. This includes childcare and any other caring responsibility you have, provided:
You can ask for up to £1,000 per person for each conference.
Collaborative travel
We provide travel and subsistence costs for you and any research staff employed on your grant for UK and overseas visits to collaborators, and for collaborators to visit your laboratory. You’ll need to justify each visit and its duration.
Other travel
We will pay for other essential visits, for example to facilities, for sample collection and for fieldwork. You can include subsistence costs.
Carbon offset costs
This is a new policy. It applies to all types of travel costs Wellcome provides.
You can ask for:
We won't pay for the core infrastructure that your host organisation should provide, unless you're eligible to ask for these costs under our overheads policy. Examples of these costs include:
See our carbon offset policy for travel for information on what you and your organisation need to do.
Subsistence costs
If you’re away for up to one month you can ask for subsistence costs. These include accommodation, meals and incidentals (eg refreshments or newspapers).
If your administering organisation has a subsistence policy, use their rates.
If your administering organisation doesn’t have a subsistence policy, please use the HMRC rates.
If you’re away for more than one month and up to 12 months, we will pay reasonable rental costs only, including aparthotels. You should discuss appropriate rates with your administering and host organisations, or Wellcome, as appropriate. We expect you to choose the most economical options, booked in advance where possible.
If you’re from a low- or middle- income country and will be working in a high-income country for more than one month and up to 12 months, you can also ask for up to £10 a day to cover extra costs, such as transport and incidentals.
If you’re away for more than 12 months, we will pay the costs of your housing. You should discuss your needs with your administering and host organisations.
The allowance we provide will be based on family and business need. We will set the maximum allowance we pay for each location. This will be based on current market data or, where data is unavailable, in consultation with your administering organisation, using equivalent market rates. Please contact us if you need help calculating the costs.
We will cover the direct expenses you have to pay to find and rent a home. We will not cover the cost of utilities or any refurbishment.
Overseas research
If you or any research staff employed on your grant will be doing research away from your home laboratory, we'll help with the additional costs of working on the project overseas. Please see the 'Overseas allowances' section for details.
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- a contribution towards the personal cost of carrying out research overseas, to ensure that you are not disadvantaged
- provided on the assumption that you’ll be paying income tax, either in your home country, or the country you will be working in (your personal tax is your responsibility).
- provided on the understanding that you or your partner will not receive equivalent allowances from elsewhere
- determined by the amount of time you will spend away from your home country.
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If you will be away more than 12 months, we will provide overseas allowances for your partner and any dependants if they are travelling with you.
If you will be away for 12 months or less and can justify why your partner and dependants must travel with you, we may provide overseas allowances for them.
We define your partner as the person:
- you’re married to
- you’re not married to but with whom you’ve been in a relationship for at least a year
and
- you live with at the same permanent address and share some form of joint financial commitment with (eg a mortgage).
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We will pay your travel costs at the beginning and end of your overseas work. Costs can be for air, ferry, train or coach fares.
All fares should be:
- in line with our carbon offset policy
- booked in advance where possible.
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If you are away for up to 12 months, you can ask for up to 80kg of additional baggage or unaccompanied airline freight for your outward and return journeys.
If you are away for more than 12 months, you can ask for the costs of shipping your personal items at the beginning and end of your overseas work.
We will pay the full cost of transporting:
- half a standard shipping container if you’re travelling alone
- a whole standard shipping container (20ft) if you’re travelling with a partner and/or dependants.
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We will pay the cost of your medical insurance and travel insurance.
If you will be working in a low- or middle-income country we will also cover the cost of emergency evacuation cover.
We won’t pay for medical insurance if you will be based in the UK or Republic of Ireland.
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We will pay the costs of visas, vaccinations and anti-malaria treatment.
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You can ask for this if you’ll be based in a low- or middle-income country and it is necessary.
Costs can include guards, panic buttons and alarms. You should ask your employing organisation for advice on the level of security you need.
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If you’re away for up to one month you can ask for subsistence costs. These include accommodation, meals and incidentals (eg refreshments or newspapers).
If your administering organisation has a subsistence policy, use their rates.
If your administering organisation doesn’t have a subsistence policy, please use the HMRC rates.
If you’re away for more than one month and up to 12 months, we will pay reasonable rental costs only, including aparthotels. You should discuss appropriate rates with your administering and host organisations, or Wellcome, as appropriate. We expect you to choose the most economical options, booked in advance where possible.
If you’re from a low- or middle- income country and will be working in a high-income country for more than one month and up to 12 months, you can also ask for up to £10 a day to cover extra costs, such as transport and incidentals.
If you’re away for more than 12 months, we will pay the costs of your housing. You should discuss your needs with your administering and host organisations.
The allowance we provide will be based on family and business need. We will set the maximum allowance we pay for each location. This will be based on current market data or, where data is unavailable, in consultation with your administering organisation, using equivalent market rates. If you need help calculating the costs please contact Grants Management.
We will cover the direct expenses you have to pay to find and rent a home. We will not cover the cost of utilities or any refurbishment.
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If you’re away for more than 12 months we will pay:
Local nursery or school fees
You can ask for these costs if you are in a location where there isn’t free local education of the same standard as in your home country.
Costs include:
- local nursery school fees up to a maximum of 30 hours a week for 3 to 4 year olds
- local junior or secondary school fees, up to the end of secondary school education.
Local international school fees
You can ask for these costs if local schools do not provide the same standard of education as in your home country. We will only pay the published termly school fees.
We will not cover the costs of:
- extracurricular activities, including field trips
- other extras including, but not limited to, uniforms, sports kit and equipment, transport, meals, books and electronic equipment.
Boarding school fees
We will consider paying the cost of boarding school fees in your home country if:
- a local international school is not available
- both parents, guardians or the sole care giver live outside the home country.
The allowance covers:
- up to a maximum of £30,000 a year for each child for the published termly fees only
- the cost of return airfares at the start and end of each school term, in line with our carbon offset policy for travel.
We will not cover the costs of:
- additional annual leave airfares
- extracurricular activities, including field trips
- other extras including, but not limited to, uniforms, sports kit and equipment, transport, meals, books and electronic equipment.
We will cover the cost of providing special needs education as far as possible. Please contact us to discuss your needs.
We would not usually expect to provide an education allowance if you will be working in a high-income country.
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If you will be away for more than 12 months, we’ll pay for you to travel back to your home country for annual leave. This is in addition to your outward and return travel costs and depends on how long you will be away:
- 12-24 months – 1 annual leave trip
- 25-36 months – 2 annual leave trips
- 37-48 months – 3 annual leave trips
- 49-60 months – 4 annual leave trips
- 61-72 months – 5 annual leave trips.
All fares should be:
- in line with our carbon offset policy
- booked in advance where possible.
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If you will be away for more than 12 months, you can ask for up to 100 hours of lessons in the local language for you and/or your partner during the first 12 months of your visit.
We will cover 100% of the costs for local language school classes or up to 50% of the costs of individual tuition.
We will not cover the cost of examinations or personal learning materials such as DVDs and books.
If you or any staff employed on your grant will be spending time in another country, we’ll help you with the additional costs of working on the project overseas.
Our overseas allowances are:
Carbon offset costs
We expect the people we fund to choose travel that has a lower carbon impact, where practical, even if it’s more expensive (for example travelling by train instead of flying).
You can ask for costs to offset the carbon generated by the travel, as part of your overseas allowances.
See our carbon offset policy for travel for information on what you and your organisation need to do.
See a list of low- and middle-income countries, as defined by the Organisation for Economic Co-operation and Development (OECD).
You can ask for the following allowances. You need to provide estimated costs as accurately as possible.
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We cover fieldwork costs if they’re essential and you can justify them. Costs can include:
- survey and data collection, including communication and data collection services and any associated costs such as essential field materials, travel costs and language translation services
- the purchase, hire and running costs of vehicles dedicated to your project
- expenses for subjects and volunteers, including the recruitment of participants, their participatory fees and travel costs
- statistical analysis.
You can ask for other fieldwork costs that aren’t listed here, but you’ll need to justify them.
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We will add an inflation allowance to your award.
How we calculate your inflation allowance
Your inflation allowance is based on your total eligible costs and the duration of the award. You'll receive the following allowance if the costs in your application are in pounds sterling, euros or US dollars.
Award duration (in months) Inflation allowance 0-12 0.0% 13-24 1.0% 25-36 2.0% 37-48 3.0% 49-60 4.1% 61-72 5.1% 73-84 6.2% These rates are calculated using compound inflation at 2.0% a year from Year 2 onwards.
If your costs are in any other currency, we will use an inflation allowance that reflects the inflation rate of the country where the host organisation is based.
What to include in your application
The costs in your application must be based on current known costs, excluding inflation.
You should allow for salary pay awards during Year 1. These should be based on pay awards already agreed; if you don’t know what the pay award is yet then use our inflation rate.
Wellcome's studentship stipend scales for non-clinical/basic science PhD studentships include an annual increase for inflation.
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If your organisation receives block funding, you can ask them to cover your open access article processing charges.
If you're at an organisation that doesn't receive block grant funding, we’ll supplement your grant when your paper has been accepted for publication.
You can't ask for these charges in your grant application.
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If you need to carry out clinical trials or research using NHS patients or facilities, we will cover some of the research costs.
Annex A of the guidelines for attributing the costs of health and social care research and development (AcoRD) sets out the costs we cover, and which costs should be funded through the Department of Health in England, or its equivalent in Northern Ireland, Scotland and Wales. If you're based in the Republic of Ireland, we would expect you to adhere to the spirit of these principles.
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This supplement is to help with start-up and relocation costs during your first year. You can be a citizen of any country (including the UK) but to be eligible you must be:
- living outside the UK or Republic of Ireland when you apply
- moving to a UK organisation to take up your award.
You can't ask for this supplement if you've already accepted an offer from your host organisation.
You can also apply for this supplement if you're planning to work at one of our Africa and Asia Programmes. When you apply:
- you must be living outside the UK, the Republic of Ireland or the country where the programme is based
- the award must be held at an eligible UK organisation.
What we offer
You or your host organisation can ask for up to £500,000. We expect your host organisation to match the amount being requested. You should talk to your organisation about this.
We cover costs that aren't typically provided by this funding scheme, such as:- start-up laboratory costs
- costs for relocation of animals or major equipment
- large-scale laboratory refurbishment
- relocation expenses for you and members of your research team.
The matching contribution from your host organisation:
- can cover costs that employers are usually responsible for (see costs below)
- must not come from funds that we've already awarded to your host organisation.
What we don't offer
We don't cover costs that employers are usually responsible for, such as:
- supplementary pensions or other retirement benefits
- housing costs
- tuition fees for your children's education
- health insurance
- helping your spouse find employment.
How to apply
Please provide details of the costs you're asking for. Don't include the contribution from your host organisation.
Your host organisation's letter of recommendation must include confirmation from the vice chancellor that they will match this amount.
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Costs you may ask for (you will have to justify these costs in your application):
- specialist publications that are relevant to the research and not available in institutional libraries
- consultancy fees
- expenses for subjects and volunteers – includes recruitment of participants, their participatory fees and travel, as well as interviewee expenses
- reasonable research-associated costs related to the feedback of health-related findings but not any healthcare-associated costs
- costs associated with developing an outputs management plan
- questionnaires, recruitment material, newsletters etc for clinical, epidemiological and qualitative research studies
- public engagement materials where dissemination (including printing and publishing) is a key activity of the project
- recruitment, advertising and interviewee travel costs for staff to be employed on the grant
- formal transferable skills and personal development training, including the International Funders Award
- purchase, hire and running costs of project-dedicated vehicles.
Costs we won’t pay:
- estates costs – such as building and premises costs, basic services and utilities. This also includes phone, postage, photocopying and stationery, unless you can justify these within a clinical or epidemiological study.*
- page charges and the cost of colour prints
- research, technical and administrative staff whose time is shared across several projects and isn’t supported by an audit record*
- PhD stipends
- charge-out costs for major facilities* – departmental technical and administrative services, and use of existing equipment
- cleaning, waste and other disposal costs*
*We will fund these costs in the case of animal-related research.
- indirect costs – this includes general administration costs such as personnel, finance, library, room hire and some departmental services
- office furniture, such as chairs, desks, filing cabinets, etc.
- clothing such as lab coats, shoes, protective clothing
- non-research related activities, eg catering, room and venue hire for staff parties, team-building events and social activities
- indemnity insurance (insurance cover against claims made by subjects or patients associated with a research programme)
- ethics reviews, unless you are in a low- or middle-income country
- radiation protection costs.
Costs grantholders can claim on biomedical science research grants.
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You can also apply for Research Enrichment funding to increase the impact of your work through activities in public engagement and diversity and inclusion.
If you’re awarded this fellowship
If you’re from outside the UK, and your host organisation is in the UK, you're guaranteed an endorsement of a Tier 1 Global Talent visa application.
If you have team member(s) who will spend at least 50% of their working time contributing to the award, they may be eligible to apply for a Tier 1 visa through the endorsed funder route.
What we don’t offer
We don't fund overheads.
Stages of application
Contact us with your full CV and a brief outline of your plans
This scheme is closing. The final deadline for full applications is 1 July 2021. Please send your full CV to a head of department in one of our Science teams as soon as possible.
If you're based at a host organisation in the Republic of Ireland, you must get a letter of endorsement from Science Foundation Ireland (SFI) and/or the Health Research Board (HRB) before submitting your preliminary application. Please make sure you contact SFI and/or the HRB at least eight weeks before you submit your preliminary application.
Submit your preliminary application
View the Sample preliminary application form for Principal Research Fellowships [PDF 140KB]
Get some tips to help you write a Wellcome grant application.
We'll assess your eligibility and give advice about your competitiveness and the resources you've requested. We will give you a decision within three weeks of the preliminary application deadline. If suitable, we'll invite you to submit a full application.
Submit your full application to your host organisation for approval
Complete the full application form on Grant Tracker. Submit it to the 'authorised organisational approver' at your host organisation for approval.
If your proposal involves clinical research using NHS resources, check if you need to upload a SoECAT form with your full application.
Host organisation reviews your application and submits it to us
Scientific review and shortlisting
One of the following expert review groups will review your application, depending on your area of research:
- Cell and Developmental Biology
- Cellular and Molecular Neuroscience
- Cognitive Neuroscience and Mental Health
- Genetics, Genomics and Population Research
- Immune System in Health and Disease
- Molecular Basis of Cell Function
- Pathogen Biology and Disease Transmission
- Physiology in Health and Disease
- Population and Public Health
If successful, we will invite you for an interview. We’ll give you at least two weeks’ notice.
External Peer Review
We'll seek written comments from external expert reviewers. Unattributed comments will be sent to you before your interview.
Funding decision
Due to COVID-19, we are not holding interviews. Candidates will be contacted with further details about the decision-making process.
Disabled applicants
If you are disabled or have a chronic health condition, we can support you with the application process.
Coronavirus (Covid-19)
What you need to know if you're a grant applicant or grantholder.
Dates
This scheme will close in 2021. You can express an interest in this award at any time but the final deadline for submitting full applications is 1 July 2021.
Grants awarded
Find out about some of the people and projects we've funded for this scheme.
Contact us
If you have a general question about this scheme, contact our information officers:
If you have a question about the scope and content of your proposal, contact the relevant person in one of our science teams:
Find a contact in our science teams