Mechanisms that regulate T cell responses and their failure in autoimmunity

Grantholders

  • Prof Rose Zamoyska

    University of Edinburgh, United Kingdom

Project summary

Autoimmune diseases are those in which dysregulation of immunity leads to attack of body tissues. Professor Zamoyska will examine the cell-signalling events that underpin the regulation of autoimmune T cells, with particular focus on PTPN22, a gene that has been implicated in several human autoimmune diseases.