From evidence to progress: renewed global governance on AMR
Antimicrobial resistance (AMR) threatens the effectiveness of modern medicine and poses a growing risk to global health. Despite progress in research, surveillance and national action plans, the global response remains fragmented and lacks the coordination needed to drive lasting change.
In 2024, the UN General Assembly High-Level Meeting on AMR marked a pivotal moment, calling for a reformed and reinvigorated global governance system. This report outlines how new and existing governance structures can work together to drive sustainable, evidence-based action on AMR.
- Published:
- 18 September 2025
- Strategic programme:
- What's inside:
- This report outlines the governance model that is required to support sustainable and impactful action on AMR at national, regional and global levels
- Who this is for:
- Policymakers
- Creative commons:
Summary
Wellcome's vision is for a global governance system that is:
- evidence-led - using research to guide priorities and track progress
- inclusive - supporting countries with the highest AMR burden and addressing global power imbalances
- integrated - aligning AMR with broader global health agendas
The full report provides a more detailed exploration of how each of the following governance functions should work together and contribute to a stronger global response to AMR:
- Independent Panel on Evidence for Action against AMR (IPEA)
- Global Leaders Group on AMR (GLG)
- AMR Multi-Stakeholder Partnership Platform (MSPP)
- Quadripartite and Joint Secretariat
- Biennial AMR Ministerial Meetings
Key messages
The global response to AMR must be strengthened through coordinated governance and sustained political commitment.
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Conclusion
A renewed global governance system is essential to tackling AMR effectively.
With clearly defined roles, the system must prioritise support for countries with the highest AMR burden. It must also ensure that evidence is firmly embedded into decision making, and that AMR is integrated into broader health agendas.
With the right structures in place, global action on AMR can be more inclusive, impactful and sustainable.
Contact us
If you have any questions or comments, please contact Rebecca Manaley, Policy Advisor: