Validation and feasibility of a novel, simple and rapid assay to detect cholera in resource-poor settings and outbreak situations

A rapid diagnostic test (RDT) that is simple, sensitive and specific would be highly valuable for the early confirmation of cholera outbreaks and identifying the hotspots in endemic settings. The current diagnostic tests are either not suitable for endemic settings or have unacceptable performance. 

We have developed a novel, rapid, simple assay C-RLDT which is sensitive and specific and can be applied in resource-poor settings. 

We believe C-RLDT is an ideal tool for early detection of cholera outbreaks and disease surveillance in endemic countries. We propose to validate the novel assay and determine performance in the endemic and outbreak settings in Uganda, Zambia and Cameroon.