Synaptic neurology

Professor Kullmann's interests centre on the mechanisms that underlie normal and abnormal excitability of nerve and muscle. Much of his research addresses the basic properties of synapses in the central nervous system, synaptic plasticity, and the biophysical consequences of inherited mutations of ion channels implicated in neurological disease. Professor Kullmann is using his award to address a number of questions about how synapses work, their complement of ion channels, how dysfunction leads to diseases and what this may tell us about treatments, and how interneurons underpin information processing and memory storage.