RNA-binding proteins in health and disease
Year of award: 2011
Grantholders
Prof Javier Caceres
MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine
Project summary
Professor Caceres will be studying the roles of RNA-binding proteins involved in gene expression, a process that leads to the production of proteins and small RNA products through transcription, RNA splicing and translation. As there is a wide variety of RNA-binding proteins, each with a unique binding activity to RNA, these proteins have a profound effect on gene expression networks in cells, making them highly significant to normal and disease-related biology. The work will contribute to a better understanding of the fundamental biological processes involved in gene expression.