Novel Non-invasive Haemodynamic Methods in Heart Failure with Preserved Ejection Fraction

Heart failure with preserved ejection fraction (HFpEF) is common and becoming one of the leading causes of death in patients with heart disease. Current non-invasive tests are not accurate enough to detect or diagnose HFpEF. This results in delayed diagnosis and early death for thousands of patients. I have developed cutting-edge, fast four-dimensional flow (4D flow) magnetic resonance imaging (MRI) techniques which can reliably assess three-dimensional blood-flow inside the heart over-time (the fourth dimension). I have also invented 4D flow MRI methods that can better detect raised pressures inside the heart associated with HFpEF. It requires no additional equipment, risk or expense, and enables accurate diagnosis of HFpEF. Working with world-leading cardiologists, engineers, scientists and companies, my ambition for the Fellowship is to further develop 4D flow MRI methods that will help doctors better detect; diagnosis and provide early treatment to patients with HFpEF and hence save thousands of lives.