Mechanisms of genotype-phenotype relationships through a combination of designed perturbations and quantitative genetic interaction mapping

Tina will use her Fellowship to study how genetic perturbations affect protein-protein interactions using functional genomics, biochemistry and bioinformatics. Her mentors are Professor Tanja Kortemme at the University of California, San Francisco, and Janet Thornton at the European Bioinformatics Institute, Cambridge. Tina will also collaborate, on the functional genomics side of the project, with Professor Nevan Krogan's group at the University of California, San Francisco.