Mechanisms and decisions in microtubule-based intracellular transport
Year of award: 2014
Grantholders
Dr Anthony Roberts
Birkbeck, University of London
Project summary
Anthony's research focuses on the action of motor proteins; specialised proteins that travel inside cells and help them organise their contents, move, divide and respond to signals. His group within the Institute of Structural and Molecular Biology at Birkbeck/University College London uses structural biology and single-molecule techniques to ask mechanistic questions, such as: how do motor proteins move? How are they regulated in living cells? How and why does their malfunction give rise to human diseases such as neurodegeneration?