Influence of host genetics and Mycobacterium tuberculosis strain variation on macrophage function and TB clinical outcome


  • Dr Thuong Nguyen

    Hospital for Tropical Diseases

Project summary

Thuong is a geneticist with research interests in human genetics and macrophage function in tuberculosis. During her Fellowship, she is studying the interactions of macrophage and Mycobacterium tuberculosis under the impact of genetic variants of both human host and bacterial pathogens. This will contribute to our understanding of the pathogenesis of tuberculosis, particularly the development from localised pulmonary to disseminated disease. Thuong is based at the Oxford University Clinical Research Unit in Vietnam, working with Dr Sarah Dunstan and Dr Maxine Caws and collaborating with Professor Thomas Hawn at the University of Washington.

This grant was awarded under the scheme's previous name of Training Fellowships in Public Health and Tropical Medicine.