Immunomatrix in Complex Disease (ICD)

Grantholders

  • Prof Tracy Hussell

    University of Manchester

Project summary

Immune and inflammatory processes underlie virtually all major human diseases. Similarly, dysregulation of the extracellular matrix (ECM) is a central process in the pathogenesis of chronic diseases. However, matrix biology and immunology are typically studied independently and progress in understanding and treating disease is hindered by the complexity of tissues and the immune system. 

We will train a new generation of scientists to embrace tissue and disease complexity. By understanding the inter-connectivity between matrix and immune function they will make discoveries that help unravel complex disease. The programme will provide an intensive taught component of immunomatrix, tissue complexity and multimorbidity. There will also be a bespoke training programme in bioinformatics. We will offer intellectually challenging cross-disciplinary PhD projects using state-of-the art technology. We will enrich the student experience through optional ‘silo switches’ into allied careers. We will also provide active mentoring and the experience of mentoring others.