Functional genomics in multiple sclerosis

Multiple sclerosis (MS) is a common chronic inflammatory and neurodegenerative disease of the central nervous system. Susceptibility to MS is inherited to a certain extent, but it is not clear which genes confer this risk and how they do so. Professor Fugger will employ a multidisciplinary approach to investigate the genetic association in MS. His goal is to validate candidate genes associated with the disease, clarify their functional roles, and assess how this knowledge can be translated into novel therapeutic approaches to treat MS.