From molecules to pandemics: multi-level adaptation of human chronic viruses

Year of award: 2015


  • Dr Katrina Lythgoe

    University of Oxford

Project summary

Katrina works on the evolutionary epidemiology of chronic viral infections such as HIV and hepatitis C. She is particularly interested in disentangling the often-conflicting selection pressures that occur at the within- and among-host scales, and how these pressures impact the evolution of these viruses in the face of different intervention strategies. She uses a range of methods including mathematical modelling, stochastic simulations, and the analysis of deep-sequencing data. Previously, Katrina held a Wellcome Trust Career Re-entry Fellowship, and prior to her return to research she was the Editor of Trends in Ecology & Evolution for seven years.