Elucidating the aetiology of psychopathology: taking a multigenerational approach to genetically informative data

Year of award: 2015


  • Dr Tom McAdams

    King's College London

Project summary

Tom's research falls into the fields of developmental psychopathology, quantitative genetics, and psychiatric epidemiology. He is interested in the use of genetically informative datasets to understand the intergenerational transmission of psychopathology – how and why mental health problems run in families. Previously Tom has used children-of-twins datasets to study the impact of parental depression and anxiety on child emotional development. During his Fellowship Tom will be further developing the statistical models used to analyse such data. He will also extend his work into population databases and multigenerational genomic datasets in order to better understand the mechanisms underlying intergenerational transmission.