Cyclin B1, critical regulator of cell division
Year of award: 2012
Grantholders
Dr Suzanne Madgwick
Institute for Cell and Molecular Biosciences
Project summary
Suzanne will carry out her Fellowship in the laboratories of Professor Michael Whitaker and Dr Mark Levasseur, as a member of the Cell Signalling group at Newcastle University's Institute for Cell and Molecular Biosciences. She will be investigating the control of metaphase exit, primarily in meiotic cells, but also in mitotic cells. Female meiotic cells have a particularly high frequency of chromosome division error, often resulting in a chromosome imbalance. A comparative study of both types of cell division will not only improve our understanding of their differential control, but also provide further insight into the origins of cell division error.