Controlling emergent Anopheles stephensi in Ethiopia and Sudan (CEASE)
Year of award: 2020
Grantholders
Prof Martin Donnelly
Liverpool School of Tropical Medicine, United Kingdom
Dr David Weetman
Liverpool School of Tropical Medicine, United Kingdom
Dr Thomas Churcher
Imperial College London, United Kingdom
Dr Anne Wilson
Liverpool School of Tropical Medicine, United Kingdom
Prof Koen Peeters
Institute of Tropical Medicine (ITM), Belgium
Dr Endalamaw Belachew
Armauer Hansen Research Institute, Ethiopia
Dr Hmooda Kafy
Primary Health Care Board, Nigeria
Prof Delenasaw Yewhalaw
Jimma University, Ethiopia
Elfatih Malik
University of Khartoum, Sudan
Dr Luigi Sedda
Lancaster University, United Kingdom
Project summary
Malaria in Africa is mainly a rural disease because the local malaria mosquito species are not well adapted to urban settings. Unfortunately, current efforts to control malaria are threatened by a new, invasive mosquito species called Anopheles stephensi which has been identified in towns and cities in the Horn of Africa, including Ethiopia and Sudan and is associated with an increase in malaria in Djibouti. This research aims to control the spread of Anopheles stephensi in Sudan and Ethiopia. We will:
1) Discover the current distribution of the mosquito and route of introduction using mosquito sampling, genetic ancestry analysis and spatial modelling.
2) Determine whether Anopheles stephensi is associated with increased malaria using health system data, prospective studies to identify malaria cases, and mathematical models.
3) Identify social and ecological factors which influence the spread/control of Anopheles stephensi and will define the most appropriate mosquito control strategies.