Are longer healthy lives a flip of a switch away? A forward genetic screen of the dietary restriction response


  • Dr Mirre Simons

    University of Sheffield

Project summary

Dietary restriction is one of the most reliable ways, across species, to extend healthy lifespan. The physiological mechanisms of dietary restriction have remained highly elusive, however, precluding any translation of these promising findings to our own species. Mirre will use genetics together with demography of mortality in Drosophila to explore the physiological mechanisms involved. He will work in collaboration with Dr Rhonda Snook and Professor David Strutt (University of Sheffield) and Professor Marc Tatar (Brown University).