3D multiscale mechanical modelling of tissue growth


  • Dr Melda Tozluoglu

    University College London

Project summary

Melda is a computational biologist working on mechanical regulation of tissue growth and shape formation. She is developing a computational model for Drosophila wing disc folding. Melda's model will make it possible to investigate the roles of mechanics in the emergence and disruption of tissue architecture, independent of biochemical effects – a task the current tools are limited at. In the long term, Melda's research will relate to medical issues such as wound healing, tissue remodelling and control of overgrowth in cancer. Residing within experimental groups, Melda is utilising novel experimental data in model development, and her model is immediately available as a tool to improve our abilities in manipulating tissue growth and form.