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An international collaboration of researchers today describe a potent new drug candidate that can clear malaria infection in mice with a single oral dose. The new compound…

This report explores the application of artificial intelligence (AI) in drug discovery.

In the war against malaria, one small corner of the globe has repeatedly turned the tide, rendering our best weapons moot and medicine on the brink of defeat. Ed Yong reports.

We need to understand the impact of Covid-19 on wider health issues to shape better public health responses and limit long-term consequences. Drug resistance is one of these…

The Surveillance and Epidemiology of Drug-resistant Infections Consortium (SEDRIC) brings together a range of international experts to share expertise and take action to…

An enzyme which allows trypanosome parasites to evade human defences is a promising new drug target, according to a study funded by the Wellcome Trust and published in 'PLOS…

Researchers have discovered a genetic variant that significantly increases the risk of carriers being allergic to a common medication for epilepsy. The study, which included…

A class of antiretroviral drugs commonly used to treat HIV, particularly in Africa and low-income countries, can cause premature ageing, according to research published today…

World leaders at the United Nations General Assembly have today committed to tackling the rise in drug resistant infections.

Researchers think cannabidiol (CBD) could offer a ground-breaking new treatment for people with psychosis. A new Wellcome-supported study could help find the answers.

Malaria parasites in western Cambodia have become resistant to artemisinin-based therapies, the first-line treatment for malaria, according to a study published in the ‘New…

A drug widely used to treat Parkinson’s disease can help to reverse age-related impairments indecision making in some older people, a study from researchers at the Wellcome…

The impact of drug-resistant infections is much higher than previously thought, as shown in a new report from the Centers for Disease Control.

For the first time, researchers have identified a new genetic link to pain offering a promising drug target to alleviate chronic pain, considered one of the leading causes of…

This report presents the results of the fifth Wellcome Monitor. It looks at findings around the British public’s perceptions of drug-resistant infections and their use of…

Hopes of at last controlling malaria in Africa could be dashed by the emergence of poor-quality and fraudulent antimalarial medicines, warn experts writing in ‘Malaria…

ChEMBLdb, a vast online database of information on the properties and activities of drugs and drug-like small molecules and their targets, launches today with information on…

Researchers at the University of Edinburgh today report a new experimental compound that can improve memory and cognitive function in ageing mice. The compound is being…

Restricting the use of antibiotics is unlikely to stop the spread of drug resistance in typhoid fever, according to a study funded by the Wellcome Trust and published in the…