Novel image-guided therapeutics to improve surgical precision and loco-regional control in Neuroblastoma

Neuroblastoma (NB) is the most common extra-cranial solid cancer in children and contributes to 15% of childhood cancer deaths. Surgery to remove NB is often incomplete and poses high risks due to the significant involvement of vital organs and vessels.
We aim to develop a novel integrated surgical platform to eliminate cancer more efficiently and safely. With the synergistic use of highly innovative optical techniques, built around a core technology of using injectable probes, we aim to:

Specifically, “light up” cancer to help the surgeon in differentiating tumour from vital organs (colour-coded surgery).

Equip the surgeon with an innovative special scanner to chase small and non-visible cancer residuals.

Kill any minimal residual cancer, left by the surgeon, using a new technology based on light.

This original approach has the potential to improve the effectiveness of surgery in eradicating solid paediatric and adult cancers, leading to better survival and fewer complications.