Multi-dimensional diagnostics for rapid detection of infectious diseases in developing countries

Year of award: 2020

Grantholders

  • Dr Pantelis Georgiou

    Imperial College London, United Kingdom

Project summary

Each year there are 50-100 million cases of dengue worldwide, and 40% of the world’s population live in affected areas. There is an urgent need for diagnostic tools able to accurately identify dengue infections at the point-of-care to ensure timely and targeted clinical management. This is especially important in lower-middle income countries, including Thailand, where access to healthcare facilities is limited. We will deliver a novel portable device that can rapidly diagnose dengue from blood and identify its serotype with very high accuracy, whilst using a cloud connected mobile phone to map the location of infection. The technology, which utilises microchip based chemical sensors, will be validated as part of a diagnostic evaluation within Thai healthcare settings. To ensure the technology is appropriate for end user requirements it will be co-designed by healthcare workers in Thailand, with guidance from the Ministry of Public Health and the Village Health Volunteer system.