A novel multidisciplinary approach to interrogate the impact of cell polarisation events on pluripotent cell fate decisions

Guillaume has started his Fellowship in the laboratory of Dr Sally Lowell, in collaboration with Professor Charles ffrench-Constant and Dr Val Wilson at the MRC Centre for Regenerative Medicine in Edinburgh. Guillaume's research goal is to understand how tissue-level asymmetries feed back onto cell fate decisions during early morphogenetic events in mammalian embryos and in cultured pluripotent cells. To this end, he is developing an ambitious approach, combining image analysis (in collaboration with Professor Badri Roysam, Cullen College of Engineering, Houston) and microfabrication techniques (working with Dr Manuel Thery, CEA, Grenoble).